Tubulin α (PT2182) mouse mAb

产品详情

产品名称

Tubulin α (PT2182) mouse mAb

产品货号

YM-A05284

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,WB,IF,ELISA

分子量

52kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:1000-5000;IF 1:100-500;ELISA 1:5000-50000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT2182

免疫原

Recombinant Protein of Tubulin alpha-1A chain. AA range: 350-451

特异性

This antibody detects endogenous levels of Tubulin α protein.

基因名称

TUBA1A

蛋白名称

Tubulin alpha-1A chain

别名

基因ID-1

7846;10376

SwissProt

Q71U36;P68363;Q9BQE3;P0DPH7;P0DPH8;Q6PEY2;P68366;Q9NY65

背景

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

细胞定位

Cytoplasmic