Myosin Heavy Chain Monoclonal Antibody(11C2)

产品详情

产品名称

Myosin Heavy Chain Monoclonal Antibody(11C2)

产品货号

YM-A05299

规格

50μL;100μL

种属反应

Human,Mouse,Rat,FruitFly,Nematode

实验应用

IF

分子量

220kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IF 1:100

组成

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

11C2

免疫原

Synthetic Peptide of Myosin Heavy Chain

特异性

The antibody detects endogenous MHC proteins.

基因名称

蛋白名称

别名

基因ID-1

SwissProt

P05976;P08590;P10916;P11055;P12829;P12882;P13533;P60660;Q02045

背景

Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.

细胞定位