CD1 Monoclonal Antibody(9H6)

产品详情

产品名称

CD1 Monoclonal Antibody(9H6)

产品货号

YM-A05307

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IHC 1:50-200;IF 1:50-200

组成

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

9H6

免疫原

Synthetic Peptide of CD1

特异性

The antibody detects endogenous CD1 proteins.

基因名称

CD1A

蛋白名称

T-cell surface glycoprotein CD1a

别名

T-cell surface glycoprotein CD1a;T-cell surface antigen T6/Leu-6;hTa1 thymocyte antigen;CD antigen CD1a;

基因ID-1

909

SwissProt

P06126

背景

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838). .