HSC70 Mouse mAb(7G12)

产品详情

产品名称

HSC70 Mouse mAb(7G12)

产品货号

YM-A05399

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,WB

分子量

73kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IHC1:50-200;WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

7G12

免疫原

Synthesized peptide derived from human HSC70

特异性

This antibody detects endogenous levels of HSC70 at Human, Mouse,Rat

基因名称

HSPA8 HSC70 HSP73 HSPA10

蛋白名称

HSC70

别名

Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 8;

基因ID-1

3312

SwissProt

P11142

背景

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

细胞定位

Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.