P27 Kip1 Mouse mAb(1A7)

产品详情

产品名称

P27 Kip1 Mouse mAb(1A7)

产品货号

YM-A05400

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,WB

分子量

27kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IHC1:50-200;WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

1A7

免疫原

Synthesized peptide derived from human P27 Kip1

特异性

This antibody detects endogenous levels of P27 Kip1 at Human, Mouse,Rat

基因名称

P27 Kip1

蛋白名称

P27 Kip1

别名

基因ID-1

SwissProt

P45627

背景

Cyclin dependent kinase inhibitor 1B(CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

细胞定位