Myd88 Mouse mAb(2H12)

产品详情

产品名称

Myd88 Mouse mAb(2H12)

产品货号

YM-A05411

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC

分子量

33kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IHC 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

2H12

免疫原

Synthesized peptide derived from human Myd88

特异性

This antibody detects endogenous levels of Myd88 at Human, Mouse,Rat

基因名称

MYD88

蛋白名称

Myd88

别名

Myeloid differentiation primary response protein MyD88

基因ID-1

4615

SwissProt

Q99836

背景

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

细胞定位

Cytoplasm . Nucleus .