GRP78/Bip Monoclonal Antibody(10C9)

产品详情

产品名称

GRP78/Bip Monoclonal Antibody(10C9)

产品货号

YM-A05461

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IHC,IF

分子量

78kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

10C9

免疫原

Synthetic Peptide of GRP78/Bip

特异性

GRP78/Bip protein detects endogenous levels of GRP78/Bip

基因名称

HSPA5

蛋白名称

78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)

别名

HSPA5;GRP78;78 kDa glucose-regulated protein;GRP-78;Endoplasmic reticulum lumenal Ca;2+;-binding protein grp78;Heat shock 70 kDa protein 5;Immunoglobulin heavy chain-binding protein;BiP

基因ID-1

3309

SwissProt

P11021

背景

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010],

细胞定位

Endoplasmic reticulum lumen . Melanosome . Cytoplasm . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390). .