PPAR Delta mouse Monoclonal Antibody(2F9)

产品详情

产品名称

PPAR Delta mouse Monoclonal Antibody(2F9)

产品货号

YM-A05489

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

IF,IHC

分子量

50kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IF 1:50-200;IHC 1:100-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

2F9

免疫原

Recombinant Protein of PPAR Delta of PPAR Delta

特异性

PPAR Delta protein detects endogenous levels of PPAR Delta

基因名称

PPARD NR1C2 PPARB

蛋白名称

PPAR Delta

别名

Peroxisome proliferator-activated receptor delta;PPAR-delta;NUCI;Nuclear hormone receptor 1;NUC1;Nuclear receptor subfamily 1 group C member 2;Peroxisome proliferator-activated receptor beta;PPAR-beta;

基因ID-1

5467

SwissProt

Q03181

背景

peroxisome proliferator activated receptor delta(PPARD) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this

细胞定位

Nucleus.