Ubiquitin mouse Monoclonal Antibody(5F1)

产品详情

产品名称

Ubiquitin mouse Monoclonal Antibody(5F1)

产品货号

YM-A05501

规格

50μL;100μL

种属反应

Human,Rat,Mouse,Pig

实验应用

WB,IF,IHC

分子量

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;IHC 1:100-200;IF 1:200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

5F1

免疫原

Synthetic Peptide of Ubiquitin

特异性

Ubiquitin protein detects endogenous levels of Ubiquitin

基因名称

蛋白名称

Ubiquitin

别名

基因ID-1

7314

SwissProt

P62979;P62987;P62988

背景

UBB (ubiquitin B) encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of UBB are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

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