Collagen II mouse Monoclonal Antibody(7F9)

产品详情

产品名称

Collagen II mouse Monoclonal Antibody(7F9)

产品货号

YM-A05530

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF

分子量

142kD

宿主

Mouse

同种型

修饰

Unmodified

推荐稀释比

IHC 1:50-300;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

7F9

免疫原

Synthetic Peptide of Collagen II

特异性

The antibody detects endogenous Collagen II protein

基因名称

COL2A1

蛋白名称

Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]

别名

Collagen alpha-1;II;chain;Alpha-1 type II collagen;[Cleaved into: Collagen alpha-1;II;chain;Chondrocalcin]

基因ID-1

1280

SwissProt

P02458

背景

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Secreted, extracellular space, extracellular matrix .