uPAR (PT2194) mouse mAb

产品详情

产品名称

uPAR (PT2194) mouse mAb

产品货号

YM-A05591

规格

50μL;100μL

种属反应

Human,

实验应用

WB,IF,ELISA

分子量

37kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

PT2194

免疫原

Synthesized peptide derived from human uPAR AA range: 100-200

特异性

This antibody detects endogenous levels of uPAR protein.

基因名称

PLAUR MO3 UPAR

蛋白名称

Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87)

别名

基因ID-1

5329

SwissProt

Q03405

背景

plasminogen activator, urokinase receptor(PLAUR) Homo sapiens This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reacti

细胞定位

Membranous