Androgen Receptor (ABT101) mouse mAb

产品详情

产品名称

Androgen Receptor (ABT101) mouse mAb

产品货号

YM-A05596

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,WB,IF,ELISA

分子量

98kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT101

免疫原

Synthesized peptide derived from human AR AA range: 27-150

特异性

The antibody can specifically recognize human AR protein.

基因名称

AR DHTR NR3C4

蛋白名称

AR

别名

AIS;Androgen receptor;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor;DHTR;HUMARA;HYSP1;KD;NR3C4;Nuclear receptor subfamily 3 group C member 4;NR3C4;Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy;SBMA;Spinal and bulbar muscular atrophy;Testicular Feminization;TFM;TFM

基因ID-1

367

SwissProt

P10275

背景

Androgen receptor (AR) is a member of the ligand response transcription regulator superfamily, which is expressed in prostate, testis and sweat gland. Upon AR binding the receptor, it stimulates androgen responsive genes transcription. AR plays an important role in the occurrence and development of prostate cancer. The higher the degree of differentiation of prostate cancer tissue, the higher the expression of AR, and the hormone treatment effect of positive prostate cancer patients is better. AR is mainly used for the detection of prostate cancer, guiding clinical treatment, and can also be used for other cancers such as esophageal cancer and breast cancer.

细胞定位

Nuclear