MED1 (PTR1203) mouse mAb

产品详情

产品名称

MED1 (PTR1203) mouse mAb

产品货号

YM-A05661

规格

50μL;100μL

种属反应

Human,

实验应用

WB,IF,ELISA

分子量

220kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Monoclonal

克隆号

PTR1203

免疫原

Synthesized peptide derived from human MED1. AA range: 650-750

特异性

This antibody detects endogenous levels of MED1 protein.

基因名称

MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2

蛋白名称

Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)

别名

Mediator of RNA polymerase II transcription subunit 1;Activator-recruited cofactor 205 kDa component;ARC205;Mediator complex subunit 1;Peroxisome proliferator-activated receptor-binding protein;PBP;PPAR-binding protein;Thyroid hormone receptor-associated protein complex 220 kDa component;Trap220;Thyroid receptor-interacting protein 2;TR-interacting protein 2;TRIP-2;Vitamin D receptor-interacting protein complex component DRIP205;

基因ID-1

5469

SwissProt

Q15648

背景

mediator complex subunit 1(MED1) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008],

细胞定位