CD8 a (PTR1338) mouse mAb

产品详情

产品名称

CD8 a (PTR1338) mouse mAb

产品货号

YM-A05678

规格

50μL;100μL

种属反应

Mouse,

实验应用

IHC,WB,IF,ELISA

分子量

30-35kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PTR1338

免疫原

Synthesized peptide derived from human CD8 a AA range: 150-235

特异性

This antibody detects endogenous levels of mouse CD8 a protein.

基因名称

CD8A MAL

蛋白名称

CD8 a

别名

T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a;

基因ID-1

925

SwissProt

P01732

背景

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

细胞定位

Membranous