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产品详情
产品名称
CD8 a (ABT155) mouse mAb
产品货号
YM-A05707
规格
50μL;100μL
种属反应
Human,
实验应用
IHC,WB,IF,ELISA
分子量
30-35kD
宿主
Mouse
同种型
IgG2a,Kappa
修饰
Unmodified
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
克降性
Monoclonal
克隆号
ABT155
免疫原
Synthesized peptide derived from human protein. AA range:100-235
特异性
The antibody can specifically recognize human CD8 protein, including two typies of dimer: αβ heterodimer or αα homodimer.
基因名称
CD8A MAL
蛋白名称
CD8 a
别名
alpha polypeptide;p32;CD_antigen=CD8a;CD8;CD8 antigen alpha polypeptide;CD8 antigen alpha polypeptide;p32;CD8 antigen, alpha polypeptide;p32;CD8a;CD8A antigen;CD8A molecule;CD8A_HUMAN;Leu2;Leu2 T lymphocyte antigen;Ly 2;Ly 35;Ly B;Ly2;Ly3;Ly35;LyB;Lyt 2.1 lymphocyte differentiation antigen;AA at 100;LYT3;MAL;OKT8 T cell antigen;OTTHUMP00000160760;OTTHUMP00000160764;OTTHUMP00000203528;OTTHUMP00000203721;p32;T cell antigen Leu2;T cell co receptor;T lymphocyte differentiation antigen T8/Leu 2;T-cell surface glycoprotein CD8 alpha chain;T-cell surface glycoprotein Lyt 2;T-lymphocyte differentiation antigen T8/Leu-2;T8 T cell antigen;T8/Leu-2 T-lymphocyte differentiation antigen
基因ID-1
925
SwissProt
P01732
背景
CD8 is a 68 kDa transmembrane glycoprotein consists of two subunits, αβ heterodimer or αα homodimer linked by a disulfide. CD8 is mainly expressed on the surface of suppress/cytotoxic T cells and NK cells. It is detected to be positive in T-cell large granular lymphocytic leukemia and subcutaneous panniculitis like T-cell lymphoma, and can be a marker for Precursor T lymphoblastic leukemia / lymphoma. CD8 is negative in Mycosis Fungoides and non-hematolymphoid neoplasms.
细胞定位
Membranous
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