Claudin 7 (ABT441) mouse mAb

产品详情

产品名称

Claudin 7 (ABT441) mouse mAb

产品货号

YM-A05722

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,WB,IF,ELISA

分子量

22kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT441

免疫原

Synthesized peptide derived from human Claudin 7 AA range: 100-211

特异性

The antibody can specifically recognize human Claudin 7 protein. In western blotting of LnCap cell lysate, the antibody can label a 22 kDa band corresponding to Claudin 7.

基因名称

CLDN7 CEPTRL2 CPETRL2

蛋白名称

CEPTR L2;CEPTRL 2;CEPTRL2;Claudin 1;Claudin 7;Claudin 9;Claudin-7;Claudin1;Claudin7;Claudin9;CLD7_HUMAN;CLDN 7;CLDN-7;CLDN7;Clostridium perfringens enterotoxin receptor like 2;CPETR L2;CPETRL 2;CPETRL2;Hs.84359

别名

CEPTR L2;CEPTRL 2;CEPTRL2;Claudin 1;Claudin 7;Claudin 9;Claudin-7;Claudin1;Claudin7;Claudin9;CLD7_HUMAN;CLDN 7;CLDN-7;CLDN7;Clostridium perfringens enterotoxin receptor like 2;CPETR L2;CPETRL 2;CPETRL2;Hs.84359

基因ID-1

1366

SwissProt

O95471

背景

Claudin 7 is a 22 kDa membrane protein, belonging to the tight junction protein family. Claudin family proteins play an important role in cell polarity, signal transduction and the pathogenesis of a variety of malignant tumors. It has been reported that compared with non neoplastic mucosal tissues, the expression of claudin 7 in laryngeal squamous cell carcinoma is down-regulated, and the expression level is related to distant metastasis, which can be used as a potential predictor of poor prognosis. Therefore, claudin 7 may be a useful immunohistochemical marker for the diagnosis, metastasis and prognosis of laryngeal cancer.

细胞定位

Membranous