Oct-2 (ABT211) mouse mAb

产品详情

产品名称

Oct-2 (ABT211) mouse mAb

产品货号

YM-A05751

规格

50μL;100μL

种属反应

Human,Mouse,

实验应用

IHC,WB,IF,ELISA

分子量

65kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT211

免疫原

Synthesized peptide derived from human Oct-2 AA range: 250-350

特异性

The antibody can specifically recognize human Oct-2 protein.

基因名称

POU2F2 OCT2 OTF2

蛋白名称

Oct-2

别名

class 2;Lymphoid restricted immunoglobulin octamer binding protein;Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;NF A2;Oct 2;Oct-2;Octamer binding transcription factor 2;Octamer-binding protein 2;Octamer-binding transcription factor 2;OTF-2;OTF2;PO2F2_HUMAN;POU domain;POU domain class 2 transcription factor 2;POU2F2;transcription factor 2

基因ID-1

5452

SwissProt

P09086

背景

Oct-2 is a B-cell transcription factor that binds to coactivator Bob. 1 to activate the transcription of immunoglobulin gene. It plays a role in the formation of germinal centers and the differentiation of B cells into plasma cells. OCT2 is highly expressed in all mature B cells and low expressed in pre-B cells, T cells and myeloid cells. It is a marker of B cell differentiation. It can be used to identify B cells and B-cell lymphoma.

细胞定位

Nuclear