NKX3.1 (ABT267) mouse mAb

产品详情

产品名称

NKX3.1 (ABT267) mouse mAb

产品货号

YM-A05777

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,WB,IF,ELISA

分子量

32kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT267

免疫原

Synthesized peptide derived from human protein. AA range:1-100

特异性

The antibody can specifically recognize human NKX3.1 protein.

基因名称

NKX3-1

蛋白名称

Homeobox protein Nkx-3.1

别名

BAPX 2;BAPX2;Homeobox protein NK-3 homolog A;Homeobox protein Nkx 3.1;Homeobox protein Nkx-3.1;Homeobox protein Nkx3.1;NK homeobox;Drosophila;family 3 A;NK homeobox family 3 A;NK homeobox, family 3, member A;NK3 homeobox 1;NK3 transcription factor homolog A;NK3 transcription factor related locus 1;NKX 3;Nkx 3.1;NKX 3A;NKX3 1;NKX3;Nkx3-1;NKX3.1;Nkx3.1, Mouse, homolog of;NKX31_HUMAN;NKX3A

基因ID-1

4824

SwissProt

Q99801

背景

NKX3.1 is a nuclear transcription factor and a negative regulator of the growth of prostatic epithelial cells. Its mRNA transcription level is regulated by androgens and plays an important role in the occurrence and differentiation of prostate organs and the maintenance of the function of mature organs. NKX3.1 has high sensitivity and specificity in benign prostatic hyperplasia and prostate cancer, and can be used as one of the specific markers to distinguish prostate cancer, benign prostatic hyperplasia and non prostate cancer. It is also expressed in mucous glands of testis, ureter and pulmonary bronchus.

细胞定位

Nuclear