Cytokeratin 5 (ABT051) mouse mAb

产品详情

产品名称

Cytokeratin 5 (ABT051) mouse mAb

产品货号

YM-A05787

规格

50μL;100μL

种属反应

Human,Dog,

实验应用

IHC,WB,IF,ELISA

分子量

62kD

宿主

Mouse

同种型

IgG2a,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT051

免疫原

Synthesized peptide derived from human Cytokeratin 5 AA range: 500-590

特异性

The antibody can specifically recognize human CK5 protein, and shows no cross reaction with CK6. In western blotting of A431, A549 and Hela cell lysates, the antibody can label a 58 kDa band corresponding to CK5 only in A431 cell lysates.

基因名称

KRT5

蛋白名称

Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)

别名

58 kDa cytokeRatin;CK-5;CK5;CytokeRatin-5;CytokeRatin5;DDD;DDD1;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;keRatin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;KeRatin 5;KeRatin;keRatin complex 2, basic, gene 5;keRatin, type II cytoskeletal 5;KeRatin-5;KeRatin5;KRT 5;Krt5;KRT5A;type II cytoskeletal 5;Type-II keRatin Kb5

基因ID-1

3852

SwissProt

P13647

背景

CK5 is a cytokeratin with a molecular weight of 58 kDa. In normal tissues, CK5 is expressed in squamous epithelium, germinal layer cells of some squamous epithelium, basal cells of ductal epithelium, myoepithelial cells and mesothelial cells, and almost no expression in most glandular epithelial cells. Therefore, it can be used for the differential diagnosis of squamous cell carcinoma and adenocarcinoma, mesothelioma and adenocarcinoma, as well as benign and malignant tumors of prostate, breast and salivary gland epithelium.

细胞定位

Cytoplasmic, Membranous