Glypican-3 (ABT068) mouse mAb

产品详情

产品名称

Glypican-3 (ABT068) mouse mAb

产品货号

YM-A05796

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,WB,IF,ELISA

分子量

66kD,58kD,22kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT068

免疫原

Synthesized peptide derived from human Glypican-3(GPC3) AA range: 400-500

特异性

The antibody can specifically recognize human Glypican-3 protein.

基因名称

GPC3 OCI5

蛋白名称

Glypican-3(GPC3)

别名

DGSX;Glypican proteoglycan 3;Glypican-3 [Precursor];Gpc3;GPC3_HUMAN;GTR2 2;GTR2-2;Heparan sulphate proteoglycan;Intestinal protein OCI 5;Intestinal protein OCI-5;MXR7;OCI 5;OCI-5;OCI5;SDYS;Secreted glypican-3;SGB;SGBS;SGBS1

基因ID-1

2719

SwissProt

P51654

背景

Glypican 3 is a carcinoembryonic protein and belongs to the heparan sulfate polysaccharide family. It is mainly expressed in fetal liver, kidney and trophoblast, but not in other normal tissues. Glypican 3 is a sensitive and specific marker of hepatocellular carcinoma. Its expression is related to differentiation. The lower the degree of differentiation, the higher the expression. It is highly expressed in ovarian yolk sac tumor, choriocarcinoma and melanoma.

细胞定位

Cytoplasmic