p40 (ABT-P40) mouse mAb

产品详情

产品名称

p40 (ABT-P40) mouse mAb

产品货号

YM-A05852

规格

50μL;100μL

种属反应

Human,Mouse,

实验应用

IHC,WB,IF,ELISA

分子量

77kD,69kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein G

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT-P40

免疫原

Synthesized peptide derived from human p40 AA range: 1-100

特异性

This antibody detects endogenous levels of p40 protein.

基因名称

TP63 KET P63 P73H P73L TP73L

蛋白名称

p40

别名

基因ID-1

8626

SwissProt

Q9H3D4

背景

tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim

细胞定位

Nuclear