Cytokeratin 13 (ABT-CK13) mouse mAb

产品详情

产品名称

Cytokeratin 13 (ABT-CK13) mouse mAb

产品货号

YM-A05911

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,ELISA

分子量

50kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT-CK13

免疫原

Synthesized peptide derived from human Cytokeratin 13 AA range: 400-458

特异性

The antibody can specifically recognize human CK13 protein.

基因名称

KRT13

蛋白名称

Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)

别名

基因ID-1

3860

SwissProt

P13646

背景

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasmic, Membranous