Cytokeratin 18 (ABT-CK18) mouse mAb

产品详情

产品名称

Cytokeratin 18 (ABT-CK18) mouse mAb

产品货号

YM-A05913

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,ELISA

分子量

48kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT-CK18

免疫原

Synthesized peptide derived from human Cytokeratin 18 AA range: 200-300

特异性

The antibody can specifically recognize human CK18 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 17, 19, 20.

基因名称

KRT18 CYK18 PIG46

蛋白名称

Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)

别名

基因ID-1

3875

SwissProt

P05783

背景

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasmic, Membranous