Cytokeratin 6 (ABT052) mouse mAb

产品详情

产品名称

Cytokeratin 6 (ABT052) mouse mAb

产品货号

YM-A05915

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,ELISA

分子量

60kD

宿主

Mouse

同种型

IgG2a,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT052

免疫原

Synthesized peptide derived from human Cytokeratin 6 AA range: 2-100

特异性

The antibody can specifically recognize human CK6 protein, and shows no cross reaction with CK5.

基因名称

KRT6A K6A KRT6D

蛋白名称

CK 6A;CK 6B;CK 6C;CK 6D;CK 6E;CK-6B;CK-6C;CK-6E;Cytokeratin 6a;Cytokeratin 6B;Cytokeratin 6C;Cytokeratin 6D;Cytokeratin 6E;Cytokeratin-6B;Cytokeratin-6C;Cytokeratin-6E;K2C6C_HUMAN;K6a keratin;K6b keratin;K6C;K6c keratin;K6d keratin;K6e keratin;Keratin;Keratin K6h;Keratin type II cytoskeletal 6A;Keratin type II cytoskeletal 6B;Keratin type II cytoskeletal 6C;Keratin type II cytoskeletal 6D;Keratin type II cytoskeletal 6E;Keratin-6C;KRT6A;KRT6B;KRT6C;KRT6D;KRT6E;type II cytoskeletal 6C;Type-II keratin Kb12

别名

CK 6A;CK 6B;CK 6C;CK 6D;CK 6E;CK-6B;CK-6C;CK-6E;Cytokeratin 6a;Cytokeratin 6B;Cytokeratin 6C;Cytokeratin 6D;Cytokeratin 6E;Cytokeratin-6B;Cytokeratin-6C;Cytokeratin-6E;K2C6C_HUMAN;K6a keratin;K6b keratin;K6C;K6c keratin;K6d keratin;K6e keratin;Keratin;Keratin K6h;Keratin type II cytoskeletal 6A;Keratin type II cytoskeletal 6B;Keratin type II cytoskeletal 6C;Keratin type II cytoskeletal 6D;Keratin type II cytoskeletal 6E;Keratin-6C;KRT6A;KRT6B;KRT6C;KRT6D;KRT6E;type II cytoskeletal 6C;Type-II keratin Kb12

基因ID-1

SwissProt

P02538;P04259;P48668

背景

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathoge

细胞定位

Cytoplasmic, Membranous