Fascin (ABT-FASN) mouse mAb

产品详情

产品名称

Fascin (ABT-FASN) mouse mAb

产品货号

YM-A05917

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,ELISA

分子量

55kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT-FASN

免疫原

Synthesized peptide derived from human Fascin AA range: 250-350

特异性

The antibody can specifically recognize human Fascin protein.

基因名称

FSCN1 FAN1 HSN SNL

蛋白名称

Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

别名

基因ID-1

6624

SwissProt

Q16658

背景

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

细胞定位

Cytoplasmic