Insulin (PT0156) mouse mAb

产品详情

产品名称

Insulin (PT0156) mouse mAb

产品货号

YM-A05925

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,ELISA

分子量

9kD

宿主

Mouse

同种型

IgG2a,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0156

免疫原

Synthesized peptide derived from human Insulin AA range: 25-110

特异性

The antibody can specifically recognize human Insulin protein.

基因名称

INS

蛋白名称

Insulin

别名

Insulin [Cleaved into: Insulin B chain;Insulin A chain]

基因ID-1

3630

SwissProt

P01308

背景

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

细胞定位

Cytoplasmic