Myelin Basic Protein(MBP) (ABT-MBP) Mouse mAb

产品详情

产品名称

Myelin Basic Protein(MBP) (ABT-MBP) Mouse mAb

产品货号

YM-A05961

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,ELISA

分子量

33kD

宿主

Mouse

同种型

IgG1,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT-MBP

免疫原

Synthesized peptide derived from human Myelin Basic Protein(MBP) AA range: 150-250

特异性

The antibody can specifically recognize human Myelin Basic Protein.

基因名称

MBP

蛋白名称

Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)

别名

基因ID-1

4155

SwissProt

P02686

背景

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that

细胞定位

Cytoplasmic