Caldesmon (ABT125) mouse mAb

产品详情

产品名称

Caldesmon (ABT125) mouse mAb

产品货号

YM-A05999

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,ELISA

分子量

93kD

宿主

Mouse

同种型

IgG2a,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT125

免疫原

Synthesized peptide derived from human Caldesmon pan AA range: 100-200

特异性

The antibody can recognize human h-caldesmon and l-caldesmon protein.

基因名称

CALD1 CAD CDM

蛋白名称

Caldesmon pan

别名

Caldesmon;CDM;

基因ID-1

800

SwissProt

Q05682

背景

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasmic