Collagen Type II (ABT501) mouse mAb

产品详情

产品名称

Collagen Type II (ABT501) mouse mAb

产品货号

YM-A06010

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,IF,ELISA

分子量

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:50-200;IF 1:50-200;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT501

免疫原

Synthesized peptide derived from human Collagen Type II AA range: 1200-1300

特异性

The antibody can specifically recognize human Collagen Type II protein, collagen types I, III, IV and V do not respond to the anbody.

基因名称

COL2A1

蛋白名称

Collagen Type II

别名

Collagen alpha-1;II;chain;Alpha-1 type II collagen;[Cleaved into: Collagen alpha-1;II;chain;Chondrocalcin]

基因ID-1

1280

SwissProt

P02458

背景

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasmic