Nucleophosmin (ABT486) mouse mAb

产品详情

产品名称

Nucleophosmin (ABT486) mouse mAb

产品货号

YM-A06056

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

IHC,ELISA

分子量

33kD

宿主

Mouse

同种型

IgG2a,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT486

免疫原

Synthesized peptide derived from human Nucleophosmin AA range: 100-200

特异性

The antibody can specifically recognize human Nucleophosmin protein.

基因名称

NPM1 NPM

蛋白名称

Nucleophosmin

别名

Nucleophosmin;NPM;Nucleolar phosphoprotein B23;Nucleolar protein NO38;Numatrin;

基因ID-1

4869

SwissProt

P06748

背景

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009],

细胞定位

Nuclear, Cytoplasmic