PIK3CA H1047R (ABT453) mouse mAb

产品详情

产品名称

PIK3CA H1047R (ABT453) mouse mAb

产品货号

YM-A06063

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,ELISA

分子量

124kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-400;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT453

免疫原

Synthesized peptide derived from human PIK3CA H1047R AA range: 1000-1068

特异性

The antibody can specifically recognize the h1047r mutation of human PIK3CA protein, and does not react with wild-type PIK3CA protein.

基因名称

PIK3CA

蛋白名称

5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase catalytic subunit alpha isoform;caPI3K;CLOVE;CWS5;MCAP;MCM;MCMTC;MGC142161;MGC142163;p110 alpha;p110alpha;Phosphatidylinositol 3 kinase catalytic alpha polypeptide;Phosphatidylinositol 3 kinase catalytic 110 KD alpha;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform;Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha;Phosphatidylinositol-4;Phosphoinositide 3 kinase catalytic alpha polypeptide;PI 3 Kinase catalytic subunit alpha;PI3 kinase p110 subunit alpha;PI3-kinase subunit alpha;PI3K;PI3K-alpha;PI3KC A;PIK3C A;Pik3ca;PK3CA;PK3CA_HUMAN;PtdIns 3 kinase p110;PtdIns-3-kinase subunit alpha;PtdIns-3-kinase subunit p110-alpha;Serine/threonine protein kinase PIK3CA

别名

5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;5-bisphosphate 3-kinase catalytic subunit alpha isoform;caPI3K;CLOVE;CWS5;MCAP;MCM;MCMTC;MGC142161;MGC142163;p110 alpha;p110alpha;Phosphatidylinositol 3 kinase catalytic alpha polypeptide;Phosphatidylinositol 3 kinase catalytic 110 KD alpha;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha;Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform;Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha;Phosphatidylinositol-4;Phosphoinositide 3 kinase catalytic alpha polypeptide;PI 3 Kinase catalytic subunit alpha;PI3 kinase p110 subunit alpha;PI3-kinase subunit alpha;PI3K;PI3K-alpha;PI3KC A;PIK3C A;Pik3ca;PK3CA;PK3CA_HUMAN;PtdIns 3 kinase p110;PtdIns-3-kinase subunit alpha;PtdIns-3-kinase subunit p110-alpha;Serine/threonine protein kinase PIK3CA

基因ID-1

5290

SwissProt

P42336

背景

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016],

细胞定位

Cytoplasmic