CD117 (C-kit) (ABT233) mouse mAb

产品详情

产品名称

CD117 (C-kit) (ABT233) mouse mAb

产品货号

YM-A06068

规格

50μL;100μL

种属反应

Human,

实验应用

IHC,ELISA

分子量

150kD

宿主

Mouse

同种型

IgG2b,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:50-200;ELISA 1:500-5000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

ABT233

免疫原

Synthesized peptide derived from human CD117 (C-kit) AA range: 300-400

特异性

The antibody can specifically recognize human CD117 protein.

基因名称

KIT SCFR

蛋白名称

CD117 (C-kit)

别名

Mast/stem cell growth factor receptor Kit;SCFR;Piebald trait protein;PBT;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;p145 c-kit;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;CD antigen CD117;

基因ID-1

3815

SwissProt

P10721

背景

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasmic, Membranous