GAPDH (PT0004R) rabbit mAb

产品详情

产品名称

GAPDH (PT0004R) rabbit mAb

产品货号

YM-A06078

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Rabbit,Dog,Monkey,

实验应用

WB,ELISA

分子量

37kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:20000

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0004R

免疫原

Synthesized peptide derived from human protein. AA range:200-300

特异性

Endogenous

基因名称

GAPDH

蛋白名称

Glyceraldehyde-3-phosphate dehydrogenase

别名

GAPDH;GAPD;CDABP0047;OK/SW-cl.12;Glyceraldehyde-3-phosphate dehydrogenase;GAPDH;Peptidyl-cysteine S-nitrosylase GAPDH

基因ID-1

2597

SwissProt

P04406

背景

glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri

细胞定位

Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Membrane . Cytoplasm, cytoskeleton . Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). .