CD105 (PT0152R) PT® Rabbit mAb

产品详情

产品名称

CD105 (PT0152R) PT® Rabbit mAb

产品货号

YM-A06139

规格

50μL;100μL

种属反应

Human,

实验应用

WB,IHC,IF,IP,ELISA

分子量

95kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:100-200;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0152R

免疫原

特异性

Endogenous

基因名称

ENG END

蛋白名称

Endoglin (CD antigen CD105)

别名

基因ID-1

2022

SwissProt

P17813

背景

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],

细胞定位

Cytoplasm