FGFR1 (PT0155R) PT® Rabbit mAb

产品详情

产品名称

FGFR1 (PT0155R) PT® Rabbit mAb

产品货号

YM-A06142

规格

50μL;100μL

种属反应

Human,

实验应用

WB,IHC,IF,IP,ELISA

分子量

145kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:100-200;WB 1:500-2000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0155R

免疫原

特异性

Endogenous

基因名称

FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR

蛋白名称

Fibroblast growth factor receptor 1

别名

FGFR1;BFGFR;CEK;FGFBR;FLG;FLT2;HBGFR;Fibroblast growth factor receptor 1;FGFR-1;Basic fibroblast growth factor receptor 1;BFGFR;bFGF-R-1;Fms-like tyrosine kinase 2;FLT-2;N-sam;Proto-oncogene c-Fgr;CD antigen CD331

基因ID-1

2260

SwissProt

P11362

背景

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,

细胞定位

Membranous