NADPH oxidase 4 (PT0181R) PT® Rabbit mAb

产品详情

产品名称

NADPH oxidase 4 (PT0181R) PT® Rabbit mAb

产品货号

YM-A06162

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IF,IP,ELISA

分子量

67kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0181R

免疫原

特异性

Endogenous

基因名称

NOX4 RENOX

蛋白名称

NADPH oxidase 4 (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) (Renal NAD(P)H-oxidase)

别名

基因ID-1

50507

SwissProt

Q9NPH5

背景

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],

细胞定位

Cytoplasm