SIRT3 (PT0250R) PT® Rabbit mAb

产品详情

产品名称

SIRT3 (PT0250R) PT® Rabbit mAb

产品货号

YM-A06207

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

28kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0250R

免疫原

特异性

Endogenous

基因名称

SIRT3

蛋白名称

NAD-dependent protein deacetylase sirtuin-3 mitochondrial

别名

SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;Regulatory protein SIR2 homolog 3;SIR2-like protein 3

基因ID-1

23410

SwissProt

Q9NTG7

背景

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位

Mitochondrion matrix