TNF α (PT0472R) PT® Rabbit mAb

产品详情

产品名称

TNF α (PT0472R) PT® Rabbit mAb

产品货号

YM-A06322

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

18kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:2000-1:10000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0472R

免疫原

特异性

Endogenous

基因名称

TNF TNFA TNFSF2

蛋白名称

Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-doma

别名

TNF;TNFA;TNFSF2;Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a

基因ID-1

7124

SwissProt

P01375

背景

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],

细胞定位

Membrane