OCLN (PT0483R) PT® Rabbit mAb

产品详情

产品名称

OCLN (PT0483R) PT® Rabbit mAb

产品货号

YM-A06331

规格

50μL;100μL

种属反应

Human,Mouse,Rat,

实验应用

WB,IHC,IF,IP,ELISA

分子量

65kD

宿主

Rabbit

同种型

IgG,Kappa

修饰

Unmodified

推荐稀释比

IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Monoclonal

克隆号

PT0483R

免疫原

特异性

Endogenous

基因名称

OCLN

蛋白名称

Occludin;OCN

别名

基因ID-1

100506658

SwissProt

Q16625

背景

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

细胞定位

Membrane