ATX3 Polyclonal Antibody

产品详情

产品名称

ATX3 Polyclonal Antibody

产品货号

YM-A06381

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

40kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 200-280

特异性

ATX3 Polyclonal Antibody detects endogenous levels of protein.

基因名称

ATXN3 ATX3 MJD MJD1 SCA3

蛋白名称

Ataxin-3 (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)

别名

基因ID-1

4287

SwissProt

P54252

背景

ataxin 3(ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016],

细胞定位

Nucleus matrix . Nucleus . Predominantly nuclear, but not exclusively, inner nuclear matrix.