PAK6 Polyclonal Antibody

产品详情

产品名称

PAK6 Polyclonal Antibody

产品货号

YM-A06391

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

74kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 100-180

特异性

PAK6 Polyclonal Antibody detects endogenous levels of protein.

基因名称

PAK6 PAK5

蛋白名称

Serine/threonine-protein kinase PAK 6 (PAK-5) (p21-activated kinase 6) (PAK-6)

别名

基因ID-1

56924

SwissProt

Q9NQU5

背景

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

细胞定位

Cytoplasm. Nucleus. Cotranslocates into nucleus with AR in response to androgen induction.