PDE3A Polyclonal Antibody

产品详情

产品名称

PDE3A Polyclonal Antibody

产品货号

YM-A06411

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

125kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 250-330

特异性

PDE3A Polyclonal Antibody detects endogenous levels of protein.

基因名称

PDE3A

蛋白名称

cGMP-inhibited 3',5'-cyclic phosphodiesterase A (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)

别名

基因ID-1

5139

SwissProt

Q14432

背景

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],

细胞定位

Membrane ; Multi-pass membrane protein . Cytoplasm, cytosol .