AK1C4 Polyclonal Antibody

产品详情

产品名称

AK1C4 Polyclonal Antibody

产品货号

YM-A06769

规格

50μL;100μL

种属反应

Human

实验应用

WB,ELISA

分子量

35kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 1-80

特异性

AK1C4 Polyclonal Antibody detects endogenous levels of protein.

基因名称

AKR1C4 CHDR

蛋白名称

Aldo-keto reductase family 1 member C4 (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (Chlordecone reductase) (CDR) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA)

别名

基因ID-1

1109

SwissProt

P17516

背景

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol .