ACHB3 Polyclonal Antibody

产品详情

产品名称

ACHB3 Polyclonal Antibody

产品货号

YM-A07311

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

50kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 160-240

特异性

ACHB3 Polyclonal Antibody detects endogenous levels of protein.

基因名称

CHRNB3

蛋白名称

Neuronal acetylcholine receptor subunit beta-3

别名

基因ID-1

1142

SwissProt

Q05901

背景

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N

细胞定位

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.