PREX1 Polyclonal Antibody

产品详情

产品名称

PREX1 Polyclonal Antibody

产品货号

YM-A07380

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

182kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 340-420

特异性

PREX1 Polyclonal Antibody detects endogenous levels of protein.

基因名称

PREX1 KIAA1415

蛋白名称

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)

别名

基因ID-1

57580

SwissProt

Q8TCU6

背景

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1(PREX1) Homo sapiens The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.