PACS1 Polyclonal Antibody

产品详情

产品名称

PACS1 Polyclonal Antibody

产品货号

YM-A07391

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,ELISA

分子量

105kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 400-480

特异性

PACS1 Polyclonal Antibody detects endogenous levels of protein.

基因名称

PACS1 KIAA1175

蛋白名称

Phosphofurin acidic cluster sorting protein 1 (PACS-1)

别名

基因ID-1

55690

SwissProt

Q6VY07

背景

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008],

细胞定位

Golgi apparatus, trans-Golgi network . Localizes in the perinuclear region, probably the TGN. .