RB33B Polyclonal Antibody

产品详情

产品名称

RB33B Polyclonal Antibody

产品货号

YM-A07513

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

25kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 100-180

特异性

RB33B Polyclonal Antibody detects endogenous levels of protein.

基因名称

RAB33B

蛋白名称

Ras-related protein Rab-33B

别名

基因ID-1

83452

SwissProt

Q9H082

背景

This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities. [provided by RefSeq, Sep 2016],

细胞定位

Golgi apparatus membrane ; Lipid-anchor . Golgi apparatus, cis-Golgi network . Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm. .