ASPM Polyclonal Antibody

产品详情

产品名称

ASPM Polyclonal Antibody

产品货号

YM-A07997

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

IHC,IF

分子量

382kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-300;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 1230-1310

特异性

ASPM Polyclonal Antibody detects endogenous levels of protein.

基因名称

ASPM MCPH5

蛋白名称

Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)

别名

基因ID-1

259266

SwissProt

Q8IZT6

背景

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],

细胞定位

Cytoplasm . Cytoplasm, cytoskeleton, spindle . Nucleus . The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis (PubMed:19690332). Associates with microtubule minus ends (By similarity). .