ALKB3 Polyclonal Antibody

产品详情

产品名称

ALKB3 Polyclonal Antibody

产品货号

YM-A08015

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,ELISA

分子量

31kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 110-190

特异性

ALKB3 Polyclonal Antibody detects endogenous levels of protein.

基因名称

ALKBH3 ABH3 DEPC1

蛋白名称

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Alkylated DNA repair protein alkB homolog 3) (DEPC-1) (Prostate cancer antigen 1)

别名

基因ID-1

221120

SwissProt

Q96Q83

背景

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008],

细胞定位

Nucleus . Cytoplasm . Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage (PubMed:29144457). Predominantly localizes to the nucleus. .