PK1IP Polyclonal Antibody

产品详情

产品名称

PK1IP Polyclonal Antibody

产品货号

YM-A08116

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

43kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from part region of human protein

特异性

PK1IP Polyclonal Antibody detects endogenous levels of protein.

基因名称

PAK1IP1 PIP1 WDR84

蛋白名称

p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)

别名

基因ID-1

55003

SwissProt

Q9NWT1

背景

function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.,similarity:Contains 5 WD repeats.,subunit:Interacts with PAK1.,tissue specificity:Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus.,

细胞定位

Nucleus, nucleolus .